Speeding the path to synthetic jet fuel with AI, automation and biosensors
AI Summary: Researchers at the Joint BioEnergy Institute (JBEI) have developed two complementary approaches to enhance the production of isoprenol, a precursor for high-performance jet fuel. One study employs an automated pipeline combined with machine learning to engineer Pseudomonas putida strains, achieving a fivefold increase in isoprenol production. The second study repurposes the bacterium's natural fuel-sensing capabilities into a biosensor, enabling the identification of strains that produce up to 36 times more isoprenol. These advancements significantly accelerate the strain design process, moving 10 to 100 times faster than traditional methods.